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Introduction Chemical composition / key active constituents Samples of the Indian plants collected from different places showed the presence of the following glycosides: indocentelloside, brahmoside, brahminoside, asiaticoside, thankuniside and isothankuniside. The corresponding triterpene acids obtained on hydrolysis of the glycosides are indocentoic, brahmic, asiatic, thankunic and isothankunic. These acids, except the last two, are also present in free form in the plant apart from isobrahmic and betulic acids. The presence of mesoinositol, a new oligosaccharide, ‘centellose’, kaempferol, quercetin and stigmasterol, have also been reported.
Pharmacology The main active ingredients in Brahmi are Bacoside A and B. Bacoside A assists in release of nitric oxide that allows the relaxation of the aorta and veins, to allow the blood to flow more freely through the body. Therefore Brahmi is revered for strenghtening the immune system, improving vitality and performance and promoting longevity. Bacoside B is a protein valued for nourishing the brain cells, as a result Brahmi improves mental clarity, confidence, intelligence and memory recall. It has been widely used by students and older people alike.
Asiaticosides stimulate the reticuloendothelial system where new blood cells are formed and old ones destroyed, fatty materials are stored, iron is metabolized, and immune responses and inflammation occur or begin. The primary mode of action of Centella appears to be on the various phases of connective tissue development, which are part of the healing process. Centella also increases keratinization, the process of building more skin in areas of infection such as sores and ulcers. Asiaticosides also stimulate the synthesis of lipids and proteins necessary for healthy skin. Finally centella strengthens veins by repairing the connective tissues surrounding veins and decreasing capillary fragility.
Remedies For
Dosage
References: Ayurveda concentrates on the techniques of a healthy normal life.
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