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Introduction
The virtues of Aloe Vera have been recorded for
thousands of years by many ancient civilizations, including
Egypt, Persia, Greece, India and Africa. The name was derived
from the Arabic alloen meaning 'bitter' because of the bitter
liquid found in the leaves. In 1500 B.C. Egyptians recorded
use of the herbal plant in treating: burns, infections &
parasites. It is reported that Aloe was used to embalm the
body of Christ. Spanish missionaries in the west always
planted Aloe around their settlements and carried it on their
journeys to aid the sick. Chemical composition / key active constituents
Aloe Vera leaf contains major Glycosides - Anthracene
derivatives: Hydroxyanthraquinone derivatives (25-40) viz.,
aloin (=barbaloin, a mixture of aloin A & B, the
disstereoisomeric 10-C glucosides of aloe-emodin anthraone)
and 7-hydroxyaloin isomers. Minor contain includes aloe
emodin, chrysophanol, Chromone derivative viz., aloeresin B
(=aloesin, upto 30%) with its p-coumaryl derivatives
aloeresins A & C and the aglycone aloesone. The active
principle of aloe is a mixture of glycosides called aloin. The
proportion of aloin varies in different specimens of aloes.
The chief constituent of aloin is barbaloin which is a pale
yellow crystalline glycosides, soluble in water. Remedies For Pharmacology Dosage
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